Tag : CHEMOTHERAPY
In the final OS analysis of the CheckMate 816 trial, neoadjuvant nivolumab + chemotherapy significantly improved OS in patients with resectable non-small cell lung cancer (NSCLC) compared to chemotherapy alone. With median OS not reached in the nivolumab group vs. 73.7 months in the chemotherapy group , these findings underscore the potential of this combination therapy as a new standard of care.
Older cancer patients face an elevated risk of severe treatment-related toxicities (TRT), partly due to age-related physiological changes and comorbidities. However, existing tools for predicting chemotherapy toxicity have limitations in both development and practical use.
Although liver resection is the best treatment for colorectal liver metastases (CLM), only 20% of cases are initially resectable, while others require conversion chemotherapy (CTx) before undergoing secondary resection after downsizing.