Tag : CHILDREN

Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition that significantly impacts patients' quality of life (QoL). Individuals with HS often experience comorbidities, including psychiatric conditions such as depression and anxiety, with recent findings indicating they are about twice as likely to develop these disorders compared to those without HS. Secukinumab has shown sustained efficacy in moderate to severe HS in the SUNSHINE and SUNRISE phase 3 trials, improving QoL while maintaining a favorable safety profile over one year.

​The current gold standard for diagnosing food allergy (FA) is through oral food challenges (OFCs). To minimize the impact of potential allergic reactions mid-diagnosis, OFCs are performed under the presence of the appropriate equipment, trained personnel and readily available emergency treatment, which also includes constant vital signs monitoring. However, standard criteria for what vital signs to measure and how to measure them during OFCs have not been established. Hence, clinical judgment is often used as the sole determination of the outcomes of OFCs, which may lead to variability in reassessments of symptoms between clinicians and ultimately affect the final diagnosis of FA. As such, a retrospective study was conducted to compare the differences in vital signs between patients with and without allergic reactions during OFCs and identify potential vital signs that support the diagnosis of FA. During the 2024 AAAAI Annual Meeting, Dr. Elizabeth Carr from the University of Chicago, the United States, shared the results of the study.