Tag : DEXTROMETHORPHAN

  • CONFERENCE UPDATE
    Delay in relapse of Alzheimer’s disease agitation with AXS-05: The ACCORD study

    AD agitation occurs in up to 70% of AD patients and is characterized by emotional distress, aggressive behaviors, disruptive irritability and disinhibition. AD agitation is not only associated with decreased functioning and accelerated cognitive decline, but also with increased caregiver burden, earlier nursing home placement, and increased mortality. Although non-pharmacological therapies are recommended as first-line therapy for AD agitation, they are not always effective.