Tag : FLOT

Gastric cancer remains a major global health burden, ranking among the top five cancers worldwide in both incidence and mortality. Despite advances in surgery and systemic therapy, survival in locally advanced disease lags behind that of other common malignancies, such as colorectal or breast cancer.

The incidence of esophageal adenocarcinoma (EAC) is increasing, particularly in high-income countries, with almost 86,000 new cases globally in 2020. While surgery is the mainstay for cure in non-metastatic disease, multimodality treatment can improve survival in these patients.