Tag : PLASMA KALLIKREIN

Food allergy is common and can affect up to 8% of children and 10% of adults respectively, many of whom have concurrent food allergies. The allergy may require additional healthcare utilization, and their specific diets often leads to negative impacts on their nutrition, quality of life (QoL), and personal finances. Besides avoiding trigger foods and using emergency treatment when needed, there is only 1 treatment that has been approved by the Food and Drug Administration (FDA) for peanut allergy associated with burdensome therapy and high rates of adverse reactions.

Hereditary angioedema (HAE) is a rare genetic disease caused by a deficiency of the C1-inhibitor protein which causes uncontrolled plasma kallikrein activity. HAE is characterized by recurrent swelling episodes that affect the abdomen, larynx or extremities.