Tag : Subtype-based treatment

  • Functional dyspepsia (FD) is a common gut-brain interaction disorder that primarily affects adults and imposes a significant economic burden. Treatment guidelines vary, leading to inconsistencies in management approaches. A randomized, single-blinded trial was conducted to evaluate the efficacy of subtype-specific treatment vs. empirical proton pump inhibitor (PPI) therapy in adults with FD. Findings suggest that both treatment approaches significantly improved the overall symptoms and health-related quality of life (HRQoL), with no clear advantage of either, over another in FD management.

    doctor name

    Dr. Chuah Kee Huat

    Associate Professor, Consultant Gastroenterologist & Hepatologist, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

    doctor name

    Aliment Pharmacol Ther. 2025

    Chuah KH, Loo QY, Hian WX, Khoo XH, Panirsheeluam S, Mohammad Jubri N, Natarajan V, Khoo S, Mahadeva S. Clinical Trial: Treatment of Functional Dyspepsia According to Subtype Compared With Empirical Proton Pump Inhibitor. Aliment Pharmacol Ther. 2025;61(2):258-267